Analysis of ion mobility spectra for mixed vapors using Gaussian deconvolution

✍ Scribed by Dennis M Davis; Charles S Harden; Donald B Shoff; Suzanne E Bell; Gary A Eiceman; Robert G Ewing

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 744 KB
• Volume: 289
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(94)90002-r

✦ Synopsis

A central issue in the utilization of ion mobility spectrometry for chemical analysis is the proper interpretation of ion mobility spectra and the assignment of peak identities. Ion mobility spectra for contemporary drift tubes generally produce broad peaks and simple patterns without obvious details associated with structures. These features can hinder the analyses of spectra derived from mixed vapors. However, additional information from such spectra can be extracted through Gaussian deconvolutions. A deconvolution algorithm was examined for sensitivity toward parameters and for boundaries of operation using ion mobility spectra from binary mixtures. An ion-molecule cluster ion, not obvious in traditional spectra analysis, was disclosed by deconvolution analysis and confirmed by independent ion mobility spectrometry-mass spectrometry.