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Analysis of immunoglobulin genes in splenic marginal zone lymphoma suggests ongoing mutation

✍ Scribed by Deborah K. Dunn-Walters; Laurent Boursier; J.O. Spencer; Peter G. Isaacson

Book ID
117253530
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
825 KB
Volume
29
Category
Article
ISSN
1532-8392

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πŸ“œ SIMILAR VOLUMES

A unique case of IgD-only splenic margin
A unique case of IgD-only splenic marginal-zone lymphoma with mutated immunoglobulin genes: Ontogenetic implications
✍ Theodora Papadaki; Kostas Stamatopoulos; Theodore Mavrommatis; Achilles Anagnost πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 English βš– 453 KB

Splenic marginal zone lymphoma (SMZL) is a rare indolent lymphoma subtype which accounts for less than 1% of all non-Hodgkin's lymphomas. We here report a unique case of IgD-only SMZL with mutated immunoglobulin variable region genes and discuss possible ontogenetic derivation.