Analysis of IgG reactivity against human papillomavirus type-16 E7 in patients with cervical intraepithelial neoplasm indicates an association with clearance of viral infection: results of a prospective study
✍ Scribed by Tanja D. de Gruijl; Hetty J. Bontkes; Jan M.M. Walboomers; Marij J. Stukart; Antoine A.J.P. Robbesom; B. Mary E. von Blomberg-van der Flier; Paul Herbrink; Ans J. Remmink; René H.M. Verheijen; Theo J.M. Helmerhorst; Chris J.L.M. Meijer; Rik J. Scheper
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- French
- Weight
- 913 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
IgG reactivity against the immunodominant region aa6-35 of Human Papillomavirus (HPV) type-I 6 E7 was determined in a peptide-based ELISA in a cohort study of women with initial mild to moderate cervical dyskaryosis. On the basis of HPV
MATERIAL AND METHODS
Patients
CIN patients werc referred to the gynecological outpatient clinic of the Free Univcrsity Hospital in Amsterdam because of abnormal cervical cytology (mild to moderate dyskaryosis) and, after informed consent, participated in a non-intervention follow-up study carried out in a combined effort of the departments of Obstetrics and Gynecology and Pathology JTo whom correspondence and reprint requests should be addressed, at the De artment of Pathology, Free University Hos ital P.O.