Analysis of Smoothened as a candidate ge
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Jeffrey E. Ming; Bennie Jeng; Frederic J. deSauvage; Maximilian Muenke
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Article
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2002
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John Wiley and Sons
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English
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## Abstract Holoprosencephaly (HPE) is the most common structural congenital forebrain malformation in humans and is associated with mental retardation and craniofacial abnormalities. In HPE, the cerebral hemispheres fail to separate into distinct right and left halves. The condition is etiological