๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Analysis of human globin gene mutations that impair binding to the hemoglobin stabilizing protein

โœ Scribed by Yu, X.; Mollan, T. L.; Butler, A.; Gow, A. J.; Olson, J. S.; Weiss, M. J.


Book ID
118251108
Publisher
American Society of Hematology
Year
2009
Tongue
English
Weight
827 KB
Volume
113
Category
Article
ISSN
0006-4971

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Increased protein binding to a โˆ’530 muta
โœ Patricia E. Berg; Moshe Mittelman; Jacques Elion; Dominique Labie; Alan N. Schec ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 528 KB

Although some cases of the syndrome of hereditary persistence of fetal hemoglobin (HPFH) have been correlated with mutations causing a change in the binding of trans-acting factors to DNA sequences flanking the 7-globin gene, this mechanism has not been described in pthalassemias upstream of the can

Correlating disease-related mutations to
โœ Rita Casadio; Marco Vassura; Shalinee Tiwari; Piero Fariselli; Pier Luigi Martel ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 613 KB

Single residue mutations in proteins are known to affect protein stability and function. As a consequence, they can be disease associated. Available computational methods starting from protein sequence/structure can predict whether a mutated residue is or not disease associated and whether it is pro