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Analysis of hprt gene mutation following anti-cancer treatment in pediatric patients with acute leukemia

โœ Scribed by Haruyo Hirota; Masaru Kubota; Hisako Hashimoto; Souichi Adachi; Kousaku Matsubara; Katsuji Kuwakado; Yuichi Akiyama; Tsutomu Tsutsui; Haruki Mikawa


Book ID
119093791
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
637 KB
Volume
319
Category
Article
ISSN
0165-1218

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## Background: Anti-b4-blocked ricin is an immunotoxin comprised of an anti-cd19 murine monoclonal antibody (b4) conjugated to blocked ricin, which has cytotoxic activity in patients with lymphoid malignancies. ## Methods: Adults with untreated acute lymphoblastic leukemia (all) were treated with