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Analysis of HPC1, HPCX, and PCaP in Icelandic hereditary prostate cancer

✍ Scribed by Jon Bergthorsson; Gudrun Johannesdottir; Adalgeir Arason; Kristrun Benediktsdottir; Bjarni Agnarsson; Joan Bailey-Wilson; Elizabeth Gillanders; Jeffrey Smith; Jeff Trent; Rosa Barkardottir

Book ID
106136281
Publisher
Springer
Year
2000
Tongue
English
Weight
32 KB
Volume
107
Category
Article
ISSN
0340-6717

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## Abstract Three putative prostate cancer–susceptibility genes, __RNASEL/HPC1__ at 1q24, __MSR1__ at 8p22, and __ELAC2/HPC2__ at 17p11, have recently been identified. Our objective was to investigate somatic mutations in these genes in sporadic prostate cancer. We analyzed 39 clinical prostate can