Chronic hepatitis B virus (HBV) infection is a major health issue, especially in Asia. A recent genome-wide association study (GWAS) implicated genetic variants in the human leukocyte antigen (HLA)-DP locus associated with chronic hepatitis B in Japanese and Thai populations. To confirm whether the
โฆ LIBER โฆ
Analysis of HLA-DQB1 gene polymorphisms in asymptomatic HBV carriers and chronic hepatitis B patients in the Chinese Han population
โ Scribed by Z. Xi-Lin; D. Te; L. Jun-Hong; L. Liang-Ping; G. Xin-Hui; G. Ji-Rong; G. Chun-Yan; L. Zhuo; L. Ying; L. Hui
- Book ID
- 114831358
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 99 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1744-3121
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## Abstract To evaluate clinical significance of a set of SNPs of HBV core gene, a modified PCRโRFLP assay developed by Hannoun was adapted to determine HBV SNPs in 312 Chinese Han patients with chronic hepatitis B. Five typical RFLP patterns were found and named RFLP patterns C, D, E, G, and C/G m