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Analysis of HLA-DQA1 in Japanese Patients with Type 1 Diabetes Mellitus, Using DNA-PCR-RFLP Typing

✍ Scribed by Masahiro Tanaka; Jun Abe; Takao Kohsaka; Ayako Tanae


Book ID
118711724
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
468 KB
Volume
34
Category
Article
ISSN
1328-8067

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In this study HLA-DQA1 and TNF genes in addition to HLA-DQB1 gene were investigated at DNA level for elucidation of the genetic backgrounds of Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. DNA, amplified by polymerase chain reaction, was subjected to allele specific oligonucleot