Analysis of heterogeneity in human tumors: A unique role for flow and image cytometry?
โ Scribed by T. Vincent Shankey; Jia-Kuan Jin; Robert C. Flanigan; Joseph M. Pyle
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 208 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The introduction of the laser scanning cytometer offers new capabilities in cell proliferation research, through its capacity for validation of each and every cell event through direct visualization on the microscope slide. In this study, we report a direct comparison of proliferation data derived f
Flow cytometric DNA analysis is an important prognostic tool in breast cancer. We evaluated the possibility of performing DNA analysis on cell suspensions obtained by scraping the cut surface of breast tumors; 31 breast tumor nodules, including six benign and 25 malignant lesions, were studied. From
This study determined the validity of an image analysis program developed to score individual cells in human solid tumors labeled by proliferating cell nuclear antigen (PCNA) or bromodeoxyuridine (BrdUrd). The program used nuclear size, grey level, and perimeter convexity to identify cells, and eval
We previously reported an image analysis program that uses four investigator-defined parameters including two thresholds, i.e., gray-level threshold (GLT) and hue threshold (HT), to determine the number of cells (TC) and the proliferating cell nuclear antigen (PCNA) or bromodeoxyuridine (BrdUrd) lab