Analysis of Hepatitis G Virus/GB Virus C Quasispecies and Replication Sites in Human Subjects
โ Scribed by Marek Radkowski; Lian-Fu Wang; Janusz Cianciara; Jorge Rakela; Tomasz Laskus
- Book ID
- 115583739
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 82 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0006-291X
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The recently identified hepatitis G virus (HGV, also named GB virus-C, GBV-C) appears to have similarities to hepatitis C virus and other flaviviridae. To better understand its clinical significance and hepatotropism, we collected liver tissue and matched serum samples from 56 patients undergoing li
Prevalence of GBV-C/HGV was determined in a cohort of HIV-infected patients, via a reverse transcription-polymerase chain reaction detection of RNA in serum, amplifying the NS5 region of GBV-C/HGV genome. GBV-C/HGV RNA was detected in 143 (37.7%) of 379 patients, with similar results in the differen