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Analysis of growth factor signaling in genetically diverse breast cancer lines

✍ Scribed by Niepel, Mario; Hafner, Marc; Pace, Emily A; Chung, Mirra; Chai, Diana H; Zhou, Lili; Muhlich, Jeremy L; Schoeberl, Birgit; Sorger, Peter K

Book ID
125401905
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
480 KB
Volume
12
Category
Article
ISSN
1741-7007

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## Abstract The breast cancer cell line T47D produces factors which show mitogenic activity for 3T3 cells. Here we describe the partial purification of one of these factors and show that it has properties similar to plateletderived growth factor (PDGF). The T47D factor is a heat‐stable hydrophobic