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Analysis of gross deletions in the MEN1 gene in patients with multiple endocrine neoplasia type 1

✍ Scribed by Martina Owens; Sian Ellard; Bijay Vaidya


Book ID
108703929
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
197 KB
Volume
68
Category
Article
ISSN
0300-0664

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Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors in parathyroids, enteropancreatic endocrine tissues, anterior pituitary, and other tissues. The gene for MEN1 has recently been cloned and shown to code for a 610-amino acid protein of enigmatic func