Uterine leiomyomas are the most prevalent tumor type in women of reproductive age and are the most common reason for hysterectomies. Although uterine leiomyomas are considered to be benign, they are a major public health concern for women. In contrast, leiomyosarcomas are rare but highly malignant u
Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization
โ Scribed by Yan Fang; Xin-Yuan Guan; Yin Guo; Jonathan S.T. Sham; Manquan Deng; Qiwan Liang; Huimei Li; Hongen Zhang; Hang Zhou; Jeffrey Trent
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 398 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1045-2257
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To investigate the genomic imbalances associated with nasopharyngeal carcinoma (NPC), we have performed chromosome analysis by comparative genomic hybridization (CGH) on 51 tumors, including 25 primary and 26 recurrent tumors. The most common copy number increases occurred on chromosome arms 12p (59
Infiltrating lobular carcinoma (ILC) and infiltrating ductal carcinoma (IDC) are distinguished by their histopathological appearance. However, little is known about the differences in genetic changes between lobular cancers and ductal cancers. We used comparative genomic hybridization (CGH) and comp
We report genomic abnormalities identified in 14 human primary common bile duct carcinomas analyzed by cytogenetics or comparative genomic hybridization, or both. Combining the results of the two methods of analysis, 11 chromosomal arms were observed to be gained in whole or in part, and 9 chromosom