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Analysis of fludrocortisone acetate and its solid dosage forms by high-performance liquid chromatography

✍ Scribed by Therese M. Ast; Hamed M. Abdou

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
295 KB
Volume
68
Category
Article
ISSN
0022-3549

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✦ Synopsis

A newly developed reversed-phase high-performance liquid chromatographic assay and test method for determining content uniformity are described for fludrocortisone acetate. The method is stability indicating and separates most known degradation products and impurities. In addition, the method is simple, sensitive, accurate, and relatively free of interferences. The coefficient of variation for multiple weight assays is between 0.3 and 1.8%.

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