Analysis of Fenoxaprop-Ethyl and Fenoxaprop in Drinking Water Using Solid-Phase Extraction and Ion-Pair HPLC

✍ Scribed by Balinova, Anna M.

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 383 KB
• Volume: 48
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/(sici)1096-9063(199611)48:3<219::aid-ps460>3.0.co;2-i

✦ Synopsis

A method for simultaneous analysis of fenoxaprop-ethyl and its main metabolite fenoxaprop in drinking water is described. C-18 solid-phase extraction was used for pre-concentration of the analytes. Two different approaches for increasing the retention of the acidic metabolite by reversed-phase solid-phase extraction were studied: ionization suppression at low pH and ion-pairing with addition of triethylamine. The advantage of applying the ion-pairing mechanism is discussed with respect to higher recoveries obtained for fenoxaprop-ethyl. High-performance liquid chromatography with a UV detector operating at 240 nm was used for separation and detection of both compounds. Ion-pairing elution technique was applied on a C-18 reversed-phase column. The sensitivity, linearity and repeatability of the method were evaluated. The limit of determination of this method, for parent compound and metabolite, is sufficiently low for it to be used to test water samples for compliance with the European Union Drinking Water Directive.