Analysis of F2-isoprostanes as indicators of non-enzymatic lipid peroxidation in vivo by gas chromatography-mass spectrometry: development of a solid-phase extraction procedure

Measurement of Urinary F2-Isoprostanes a

Measurement of Urinary F2-Isoprostanes as Markers of in Vivo Lipid Peroxidation—A Comparison of Enzyme Immunoassay with Gas Chromatography/Mass Spectrometry

✍ Julie Proudfoot; Anne Barden; Trevor A. Mori; Valerie Burke; Kevin D. Croft; Law 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 92 KB

This study aimed at comparing the two most commonly utilized methods for measuring urinary F 2 -isoprostanes, currently considered one of the best available markers of in vivo lipid peroxidation. The F 2isoprostanes were measured in 24-h urine samples from 14 male subjects using electron capture neg