Analysis of drug resistance to HIV-1 protease using fitness function in genetic algorithm
β Scribed by A Harishchander,S Senapati,D Alex Anand
- Book ID
- 115009116
- Publisher
- BioMed Central
- Year
- 2012
- Tongue
- English
- Weight
- 129 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1471-2334
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## Abstract An βinβhouseβ recombinant virus protease inhibitor susceptibility assay was carried out (median of 3 per patient) retrospectively in 26 patients failing HIV protease inhibitor based therapy at regular intervals to the initiation of the first protease inhibitor. Patients were treated wit
## Abstract Development of drug resistance is considered a major cause for failure of antiretroviral therapy in human immunodeficiency virus type 1 (HIVβ1)βinfected patients adherent to treatment. However, the rate of emergence and the significance of HIVβ1 drug resistance in clinical practice have