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Analysis of dose fractionation in the palliation of metastases from malignant melanoma

โœ Scribed by John B. Konefal; Bahman Emami; M. V. Pilepich


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
277 KB
Volume
61
Category
Article
ISSN
0008-543X

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CDKN2A has been found mutated in melanoma families which show linkage to chromosome 9p21. In contrast, a low mutation rate has been found in melanomas, suggesting that CDKN2A might not be the first target for mutation in the development of this type of tumour. To elucidate the role of the CDKN2A gen