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Analysis of DNA oxidative damage related to cell proliferation

โœ Scribed by Paola Villani; Pier Luigi Altavista; Laura Castaldi; Giorgio Leter; Eugenia Cordelli


Book ID
117767937
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
403 KB
Volume
464
Category
Article
ISSN
1383-5718

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Catechol estrogens induce oxidative DNA
โœ Yusuke Hiraku; Naruto Yamashita; Meiko Nishiguchi; Shosuke Kawanishi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 153 KB

Estrogen-induced carcinogenesis involves enhanced cell proliferation (promotion) and genotoxic effects (initiation). To investigate the contribution of estrogens and their metabolites to tumor initiation, we examined DNA damage induced by estradiol and its metabolites, the catechol estrogens 2-hydro