Analysis of CYP1A1 induction in single cells of urothelial cell populations by flow cytometry
✍ Scribed by Sabine Plöttner; Gisela H. Degen; Peter H. Roos; Wolfram Föllmann
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 420 KB
- Volume
- 392
- Category
- Article
- ISSN
- 1618-2650
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## Abstract In the rat, expression of the __CYP1A1__ gene is closely associated with arylhydrocarbon hydroxylase (AHH) enzyme activity. AHH is an inducible enzyme activity known to play an important role in the bioactivation of polycyclic aromatic hydrocarbons (PAHs) to mutagenic and carcinogenic m