Analysis of curing of a sustained release coating formulation by application of NIR spectroscopy to monitor changes associated with glyceryl monostearate

Quality by design, part II: Application

Quality by design, part II: Application of NIR spectroscopy to monitor the coating process for a pharmaceutical sustained release product

✍ Simin Hassannejad Tabasi; Raafat Fahmy; Dennis Bensley; Charles O'Brien; Stephen 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 654 KB

Ammonio methacrylate copolymers are commercially available as Eudragit RL/RS; they differ in the degree of quaternary ammonium group substitution, which gives them different permeabilities. These closely related polymers can be combined in various ratios to control release rate; consequently, releas