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Analysis of Conformational Polymorphism in Pharmaceutical Solids Using Solid-State NMR and Electronic Structure Calculations

โœ Scribed by Smith, Jay R.; Xu, Weizong; Raftery, Daniel


Book ID
126092688
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
578 KB
Volume
110
Category
Article
ISSN
0022-3654

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AbstractรWe have been studying the artiยฎcial sweeteners aspartame (l-aspartyl-l-phenylalanine methyl ester) and neotame (N-(3,3dimethylbutyl)-l-aspartyl-l-phenylalanine methyl ester) as compounds which exhibit polymorphism. 13 C CP/MAS NMR shows that aspartame exists in three distinct forms at room