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Analysis of Competition Binding between Soluble and Membrane-Bound Ligands for Cell Surface Receptors

✍ Scribed by Li, Ping; Selvaraj, Periasamy; Zhu, Cheng


Book ID
119412160
Publisher
Biophysical Society
Year
1999
Tongue
English
Weight
230 KB
Volume
77
Category
Article
ISSN
0006-3495

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With surface plasmon resonance detection it is possible to measure the binding kinetics between a macromolecule in solution and a receptor immobilized on a sensor surface. The detector response is proportional to the mass of the analyte that binds to the surface, and therefore, a direct observation