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Analysis of collagenase and tissue inhibitor of metalloproteinase (TIMP) gene expression by cultured fibroblasts in hypertrophic scar

✍ Scribed by Mori, Yasuji; Arakawa, Masami; Hatamochi, Atsushi; Ueki, Hiroaki


Book ID
122088861
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
145 KB
Volume
8
Category
Article
ISSN
0923-1811

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The degradative effects of interleukin-1 (IL-1) on the extracellular matrix of connective tissue are mediated primarily by metalloproteinases and prostaglandins. Clinical observations suggest that these effects can be prevented, to some extent, by the use of non-steroidal anti-inflammatory drugs. We