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Analysis of clonality at the level of progenitors in chronic myelogenous leukemia using the polymerase chain reaction

โœ Scribed by Shingo Sadamura; Tsukuru Umemura; Hiroyuki Takahira; Jouji Hirata; Junji Nishimura; Hajime Nawata

Book ID
113239660
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
440 KB
Volume
16
Category
Article
ISSN
0145-2126

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## BACKGROUND. Polymerase chain reaction (PCR) based assays are becoming more reliable, simpler, and faster alternatives to traditional Southern blot hybridization (SBH) analysis for the detection of clonal immunoglobulin heavy chain (IgH) gene rearrangements. However, a variety of technical approa