Cytogenetic investigations in bone marrow from animals treated with isoniazid (INH) were performed in seven different laboratories according to a standard protocol. The experiments were carried out in the Chinese hamster, the mouse, and the rat. In short-term studies INH was administered twice at an
Analysis of chromosome aberrations in bone marrow cells of rats after treatment with isoniazid
β Scribed by A. Basler
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 88 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0340-6717
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β¦ Synopsis
100 mg INH/kg body weight was administered to male Wistar rats five times, at 24 h intervals, either intraperitoneally or intravenously. In both experimental series the yield of chromosome aberrations in bone marrow cells was not increased as compared to controls.
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