Analysis of (CAG)n size heterogeneity in
✍
Barbara Giovannone; Guglielmo Sabbadini; Luigi Di Maio; Olga Calabrese; Imma Cas
📂
Article
📅
1997
🏛
John Wiley and Sons
🌐
English
⚖ 194 KB
👁 2 views
The length of the CAG repeat responsible for Huntington disease has been analysed by two PCR methods in blood and sperm DNA of 13 expansion carriers, two carriers of intermediate alleles, and four normal subjects. The two methods consistently confirmed size heterogeneity, more pronounced in sperm an