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Analysis of apoptosis in peripheral blood and synovial tissue very early after initiation of infliximab treatment in rheumatoid arthritis patients

✍ Scribed by Carla A. Wijbrandts; Philip H. Remans; Paul L. Klarenbeek; Diana Wouters; Marius A. van den Bergh Weerman; Tom J. Smeets; Margriet J. Vervoordeldonk; Dominique Baeten; Paul P. Tak


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
246 KB
Volume
58
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To determine whether treatment with the chimeric anti–tumor necrosis factor Ξ± antibody infliximab could reduce cellularity by the induction of apoptosis in synovial tissue. ## Methods Twenty‐four rheumatoid arthritis patients with active disease were randomized to receiv

Very early treatment with infliximab in