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Analysis of apoptosis and DNA damage in bovine cumulus cells after exposure in vitro to different zinc concentrations

✍ Scribed by Anchordoquy, Juan M; Picco, Sebastián J; Seoane, Analía; Anchordoquy, Juan P; Ponzinibbio, María V; Mattioli, Guillermo A; Peral García, Pilar; Furnus, Cecilia C


Book ID
119739749
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
126 KB
Volume
35
Category
Article
ISSN
1065-6995

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## Abstract The mechanism of Cr(VI) genotoxicity has still not been elucidated. We used Fpg‐modified comet assay to assess direct‐oxidative DNA damage on human lung (A549) and bronchial (BEAS‐2B) cells exposed to 0.1, 0.5, 1.0 and 10 μm sodium chromate for 0.5, 1 and 4 h. Moreover we evaluated apop