Analysis of antiepileptic drugs in biological fluids by means of electrokinetic chromatography
β Scribed by Vincenzo Pucci; Maria Augusta Raggi
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 191 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0173-0835
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## Abstract A simple and quick gas chromatographic method has been developed for the determination of up to six commonly used antiepileptic drugs in human serum. The antiepileptics are isolated from serum by solid phase extraction on to a reversed phase sorbent and recovered with ethyl acetate as e
Sample preparation for the analysis of drugs in biological fluids consists of a number of unit operations that are used for (i) release of the drug from a conjugate or biological matrix; (ii) removal of endogenous compounds that could interfere with the assay; and (iii) techniques for liquid handlin