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Analysis of 5-fluoro-2′-deoxycytidine and 5-trifluoromethyl-2′-deoxycytidine and their related antimetabolites by high-performance liquid chromatography

✍ Scribed by Thomas V. Briggle; David A. Boothman; Carl D. Pfaffenberger; Sheldon Greer


Book ID
108449601
Publisher
Elsevier Science
Year
1986
Weight
904 KB
Volume
381
Category
Article
ISSN
0378-4347

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The behaviour of 5-methyl-2'-deoxycytidine (m 5 dCyd, claimed to be a potential marker for leukaemia) during the electrospray process was studied. In particular, considerations concerning the effect of solution chemistry (e.g. analyte concentration, pH, etc.) on electrospray ionization mass spectra