Analysis and characterization of soluble amyloid precursor protein (sAPP) across multiple CSF draws in Alzheimer's disease subjects and healthy controls

Expression patterns of β-amyloid precurs

Expression patterns of β-amyloid precursor protein (β-APP) in neural and nonneural human tissues from alzheimer's disease and control subjects

✍ Hiroyuki Arai; Virginia M.-Y. Lee; Meridith L. Messinger; Barry D. Greenberg; Da 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 861 KB

Both neural and nonneural human tissues from patients with or without Alzheimer's disease (AD) were surveyed to detect the presence of the P-amyloid protein and its precursors. This was accomplished using polyclonal and monoclonal antibodies to epitopes in the 695 amino acid long p-APP (i.e., P-APPm