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Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy

✍ Scribed by Volker M Arlt; Annie Pfohl-Leszkowicz; Jean-Pierre Cosyns; Heinz H Schmeiser


Book ID
117766737
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
196 KB
Volume
494
Category
Article
ISSN
1383-5718

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## Abstract Aristolochic acid (AA), a naturally occurring nephrotoxin and carcinogen, has been associated with the development of urothelial cancer in humans. Understanding which human enzymes are involved in AA activation and/or detoxication is important in the assessment of an individual's suscep