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Analgesic effects of nonsteroidal antiinflammatory drugs, acetaminophen, and morphine in a mouse model of bone cancer pain

✍ Scribed by Osamu Saito; Tomohiko Aoe; Tatsuo Yamamoto

Publisher
Springer
Year
2005
Tongue
English
Weight
178 KB
Volume
19
Category
Article
ISSN
0913-8668

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## Abstract The activation of microglia and astrocytes in the spinal cord is involved in the progress of cancer pain. Propentofylline (PPF), a glial modulating agent, alleviates pain hypersensitivity in neuropathic pain models. The present study investigated the potential roles of PPF in a preclini