The effects of somatostatin (SRIF) and its long-acting analogue, SMS 201-995 on the prevention and treatment of acute pancreatitis were studied in rats. Acute pancreatitis was established by ligating the bile duct at the point of entry into the duodenum, thereby allowing reflux of bile into the panc
✦ LIBER ✦
Analgesic effect of TT-232, a heptapeptide somatostatin analogue, in acute pain models of the rat and the mouse and in streptozotocin-induced diabetic mechanical allodynia
✍ Scribed by János Szolcsányi; Kata Bölcskei; Árpád Szabó; Erika Pintér; Gábor Pethő; Krisztián Elekes; Rita Börzsei; Róbert Almási; Tamás Szűts; György Kéri; Zsuzsanna Helyes
- Book ID
- 113584945
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 222 KB
- Volume
- 498
- Category
- Article
- ISSN
- 0014-2999
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## Abstract ## Objective We previously demonstrated that somatostatin (SOM) released from the activated peripheral terminals of capsaicin‐sensitive primary sensory neurons inhibits acute inflammation and nociception. This study was undertaken to examine this systemic “sensocrine” function of neuro