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Analgesic and antiinflammatory activities of the ethyl acetate fraction ofBidens pilosa(Asteraceae)

✍ Scribed by Fotso, Aurélien Fotso; Longo, Frida; Djomeni, Paul Désiré Dzeufiet; Kouam, Siméon Fogue; Spiteller, Michael; Dongmo, Alain Bertrand; Savineau, J. P.


Book ID
125361598
Publisher
Springer
Year
2013
Tongue
English
Weight
754 KB
Volume
22
Category
Article
ISSN
0925-4692

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## Abstract Reaction of ethyl 2‐(3‐pyridyl)acetate **4a** or ethyl 2‐methyl‐2‐(3‐pyridyl)acetate **4b**, with phenyl chloroformate or methyl chloroform ate, afforded the intermediate pyridinium salt **5** which undergoes regioselective nucleophilic attack at C‐4 upon reaction with a Grignard reagen