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Analgesic and antidepressive effects of low-dose amitriptyline in relation to its metabolism in patients with chronic pain

โœ Scribed by Edelbroek, Peter M; Linssen, A Corrie G; Zitman, Frans G; Rooymans, Harry G M; A, Frederik

Book ID
109844011
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
543 KB
Volume
39
Category
Article
ISSN
0009-9236

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Randomized study of sertraline and low-d
Randomized study of sertraline and low-dose amitriptyline in patients with Parkinson's disease and depression: Effect on quality of life
โœ Angelo Antonini; Silvana Tesei; Anna Zecchinelli; Paolo Barone; Danilo De Gaspar ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 74 KB ๐Ÿ‘ 1 views

We assessed the effect of 3-month treatment of sertraline (50 mg) or low-dose amitriptyline (25 mg) on depression and quality of life in 31 patients with Parkinson's disease in a prospective single-blind randomized study. Both drugs significantly reduced the Hamilton Depression Rating Scale (HDRS-17