Analgesic activity of 4-aryl-8(arylmethylene)-5,6,7,8-tetrahydrospiro[chromen-3,1'-cycloalkan]-2(4H)-ones
✍ Scribed by Kirillov, N. F.; Makhmudov, R. R.; Gavrilov, A. G.; Mardanova, L. G.
- Book ID
- 118807897
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 57 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0091-150X
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📜 SIMILAR VOLUMES
## Abstract magnified image Anhydrous zinc bromide catalysed reactions of arylidine‐3‐acetyl coumarins (**1a‐c**) and 5,6‐benzoanalogs of arylidine 3‐acetyl coumarins (**4a,4b**) with 1,3‐cyclohexanedione gives ‐(4‐aryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4__H__‐chromen‐2yl)‐2__H__‐chromen‐2‐ones (**3a, 3c**
In this study, diethylaminosulfur trifluoride (DAST) was successfully applied in monofluorination reactions of some trifluoromethyl substituted 2-hydroxy-2H-chromenones, employing a general, mild, and efficient methodology. The fluorinated compounds (2-fluoro-2H-chromenones) were synthesized as uniq