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Analgesia induced by topical application of morphine to the rat somatosensory cortex

✍ Scribed by Soto-Moyano, R.; Hernández, A.

Book ID
122560523
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
89 KB
Volume
18
Category
Article
ISSN
0304-3959

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Topical application of 0.01 or 0.1% morphine solution to the somatosensory SI area of the rat cerebral cortex significantly decreased the pain intensity rating in the formalin test without producing motor side effects or sensory deficits. Naloxone partially antagonizes this effect. Topical applicati