Anal sphincter preservation in locally advanced low rectal adenocarcinoma after preoperative chemoradiation therapy and coloanal anastomosis

Response to preoperative chemoradiation

Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma

✍ Christopher H. Crane; John M. Skibber; Barry W. Feig; Jean-Nicolas Vauthey; Howa 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 1 views

## Abstract ## BACKGROUND Although controversial, some believe that preoperative chemoradiation increases the use of sphincter‐preserving surgery in low rectal carcinoma patients. This article investigates the relationship between objective tumor response and sphincter preservation in low rectal c