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Anakinra effective in two men with Muckle-Wells syndrome


Book ID
120859491
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2003
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## Abstract Muckleโ€Wells syndrome (MWS) is a dominantly inherited autoinflammatory syndrome. Patients with MWS have a mutation in __CIAS1__, the gene encoding cryopyrin, a component of the inflammasome that regulates the processing of interleukinโ€1ฮฒ (ILโ€1ฮฒ). In this report we describe an 8โ€yearโ€old