Lyophilization of cosolvent systems may be a beneficial way of enhancing both physical and chemical stability of a drug product. The objective of this research is to establish whether cosolvent systems commonly used in the formulation of poorly watersoluble drugs can be successfully lyophilized. Pol
Anaerobic degradation of polyethylene glycol mixtures
โ Scribed by Emilia Otal; Julian Lebrato
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2003
- Tongue
- English
- Weight
- 110 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0268-2575
- DOI
- 10.1002/jctb.901
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โฆ Synopsis
Abstract
Anaerobic treatment of polyethylene glycol may represent an alternative to integrated chemicalโbiological treatment for the elimination of polyethylene glycol. Anaerobic biodegradation of synthetic waters are made with a mix of polyethylene glycol of molecular weights 400, 600 and 1000 and another made with polyethylene glycol of molecular weights 1500, 3000 and 10 000, was studied using an inoculum adapted to polyethylene glycol 10 000. The critical and minimum retention times were estimated and ranged from 13.2 to 14 and from 18 to 20 days, respectively. Under these operational conditions, the removal percentage ranged from 85 to 90%. Thus, anaerobic degradation of synthetic water containing polyethylene glycol produces removal percentages and hydraulic retention times similar to those of biodegradable wastewater tested at the same operational conditions. Copyright ยฉ 2003 Society of Chemical Industry
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