An unusual new allene cyclization reaction. Synthesis of dihydrofuran-3(2H)-ones
โ Scribed by Gange, David; Magnus, Philip
- Book ID
- 120971833
- Publisher
- American Chemical Society
- Year
- 1978
- Tongue
- English
- Weight
- 286 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
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## Cyclizations of Benzenesulfenyl Chloride Adducts with Conjugated Silyloxyenones: A New Stereoselective Reaction in the Synthesis of 4,5-Dihydrofuran-3(2H)-ones. -The title cyclization leads to intermediates such as (IV) and (IX), which can be converted to interesting furanones such as (VI). Th
Unique 1-[2H,5H-dihydrofur-3-yl]ketones have been synthesized from propargylic nitroethers via intramolecular cycloadditions involving silyl nitronates. Various substituent groups were placed on the 2 and 5 positions of the dihydrofuran rings. We examined the scope of the long-range coupling in prot