## Abstract We previously demonstrated that expression of androgen receptor (AR) by transfection of the androgenβindependent prostate cancer cell line PC3 decreases invasion and adhesion of these cells (PC3βAR) through modulation of Ξ±6Ξ²4 integrin expression. The treatment with androgens further red
An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells
β Scribed by Grant, Susan L; Hammacher, Annet; Douglas, Andrea M; Goss, Geraldine A; Mansfield, Rachel K; Heath, John K; Begley, C Glenn
- Book ID
- 110066321
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 538 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Kruppelβlike factor 5 (KLF5) is implicated in human breast cancer by frequent genomic deletion and expressional deregulation, but the molecular mechanisms by which KLF5 affects breast tumorigenesis are still unknown. This study was conducted to examine whether and how KLF5 affects the f
The responsiveness of estrogen receptor (ER)-positive breast cancer to endocrine therapy is frequently reduced in cells over-expressing c-erbB-2. Stimulation of ER suppresses c-erbB-2, indicating that estrogen controls the activity of c-erbB-2. Heregulin (HRG) has been described to bind to c-erbB-3/
In many cancer cell lines, including breast, prostate, lung, brain, head and neck, retina, and the gastrointestinal tract, opioids decrease cell proliferation in a dose-dependent and reversible manner. Opioid and/or other neuropeptide receptors mediate this decrease. We report that only the steroid-