𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An ultrastructural and biochemical study of hexachlorophane-induced fatty liver in sheep

✍ Scribed by Ian M. Reid; Graham A. Hall

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
759 KB
Volume
115
Category
Article
ISSN
0022-3417

No coin nor oath required. For personal study only.

✦ Synopsis

The administration of single or multiple oral doses of hexachlorophane to yearling sheep resulted in a periportal fatty liver. The accumulation of fat is accompanied by ultrastructural changes in the hepatocyte organelles, particularly the endoplasmic reticulum and Golgi apparatus, and by decreased serum lipid and triglyceride levels. It is suggested that an impairment in the triglyceride secretory mechanism of the liver cell may be the patho-physiological basis for fatty liver. However, the changes in the liver were not accompanied by an evidence of significant impairment of liver cell function.

πŸ“œ SIMILAR VOLUMES

Increased sinusoidal wall permeability a
Increased sinusoidal wall permeability and liver fatty change after two-thirds hepatectomy: An ultrastructural study in the rat
✍ Eugenio Morsiani; Mary Mazzoni; Arrigo Aleotti; Paolo Gorini; Daniele Ricci πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 794 KB

Accumulation of lipids in the hepatocyte cytoplasm after partial hepatectomy (PHI has long been recognized, but the mechanism behind this phenomenon is still poorly understood. In this study, rats subjected to a standard two-thirds PH showed early and marked increase in portal venous pressure (P <.0

In vivo NMR, biochemical, and histologic
In vivo NMR, biochemical, and histologic evaluation of alcohol-induced fatty liver in rat and a comparison with CCl4 hepatotoxicity
✍ John D. Hazle; Ponnada A. Narayana; Harold A. Dunsford πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 811 KB

Magnetic resonance imaging (MRI) and spectroscopy (MRS) were used to follow the time course of ethanol-induced fatty liver in a group of 10 rats fed a diet containing 12% alcohol (ethanol) over a 5-week period. The MR data consisted of T1-weighted images, in vivo 1H spectra, and in vivo T1 relaxatio

In vivo magnetic resonance (MR) study of
In vivo magnetic resonance (MR) study of fatty liver: Importance of intracellular ultrastructural alteration for MR tissue parameters change
✍ Jyh-Wen Chai; Yung-Chang Lin; Jeon-Hor Chen; Chia-Chin Wu; Chien-Pei Lee; Woei-C πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 267 KB πŸ‘ 1 views

## Abstract Fatty liver is thought to have a shorter T1 relaxation time than normal liver tissue, due to the accumulation of triglyceride. Previous studies regarding T1 and T2 relaxation times, however, show widely different results. In order to elucidate the mechanism responsible for the changes a

Adoptive transfer of regulatory T cells
Adoptive transfer of regulatory T cells in an animal model of a diet-induced fatty liver
✍ Tetsuji Fujita πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 53 KB πŸ‘ 1 views

Unless we are both studying the same sera, there is no basis of comparison. In our clinical cases and I assume their clinical series, many types of ALF were studied and we both found AMAs when we used the same method. It is also obvious that no international standardization exists, and measurements

Melatonin prevents formaldehyde-induced
Melatonin prevents formaldehyde-induced neurotoxicity in prefrontal cortex of rats: an immunohistochemical and biochemical study
✍ Ismail Zararsiz; Ilter Kus; Murat Ogeturk; Nusret Akpolat; Evren Kose; Sedat Mey πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 131 KB πŸ‘ 1 views

## Abstract This study was undertaken to investigate the protective effects of melatonin against formaldehyde‐induced neurotoxicity in prefrontal cortex of rats. For this purpose, 21 male Wistar rats were divided into three groups. The rats in Group I were used as a control, while the rats in Group