An oxazoline-mediated synthesis of formyl epoxides
โ Scribed by Saverio Florio; Vito Capriati; Renzo Luisi
- Book ID
- 103408264
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 214 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Boron azaenolates 2 and 8 from the optically active chloromethyloxazolines 1 and 7 have been found to couple with ketones in a highly diastereoselective fashion, which depends markedly upon the geometry (Z) of the azaenolates and the nature of the ligands which are present on the boron atom, in good
## Abstract The synthesis of 3โalkenyl cephalosporins 5 using an epoxide mediated Wittig reaction is described. Reduction of the 3โฒโtriphenylphosphonium cephalosporinโ1โoxide 4 followed by condensation with acetaldehyde in the presence of 1,2โepoxybutane gave, after purification, the 3โpropylidene