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An overview of the use of non-steroidal aromatase inhibitors in the treatment of breast cancer

โœ Scribed by A Buzdar


Book ID
117656963
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
76 KB
Volume
36
Category
Article
ISSN
0959-8049

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Estrogens are the major hormones supporting the growth of human breast cancer. Aromatization of androgen precursors in peripheral tissues, including the breast cancer itself, is the major source of estrogens in postmenopausal women. Therefore, inhibition of the aromatase enzyme offers an effective m