𝔖 Bobbio Scriptorium
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An overview of the genetic analysis of complex diseases, with reference to type 1 diabetes

✍ Scribed by Glenys Thomson

Book ID
119754814
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
148 KB
Volume
15
Category
Article
ISSN
1521-690X

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πŸ“œ SIMILAR VOLUMES

Predictors of associated autoimmune dise
Predictors of associated autoimmune diseases in families with type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium
✍ Ana M. WΓ€gner; Ángelo Santana; Marta HerΕ„ndez; Julia C. Wiebe; Javier NΓ³voa; DΓ­d πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 103 KB

Background Type 1 diabetes (T1D) is a clinically heterogeneous disease. The presence of associated autoimmune diseases (AAIDs) may represent a distinct form of autoimmune diabetes, with involvement of specific mechanisms. The aim of this study was to find predictors of AAIDs in the Type 1 Diabetes G

The genetic susceptibility to type 1 (in
The genetic susceptibility to type 1 (insulin-dependent) diabetes: Analysis of the HLA-DR association
✍ E. Wolf; K. M. Spencer; A. G. Cudworth πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 725 KB

HLA-DR and MT1, MT2, MT3 genotypes have been investigated in 123 Type 1 (insulin-dependent) diabetic subjects and their families. Ninety-eight percent of probands possessed either DR3 (relative risk = 5.0), or DR4 (relative risk = 6.8) or both antigens (relative risk = 14.3), emphasizing the strong