An outbreak of hepatitis A among South African patients with hemophilia: Evidence implicating contaminated factor VIII concentrate as the source

An outbreak of hepatitis A among south a

An outbreak of hepatitis A among south african patients with hemophilia: Evidence implicating contaminated factor VIII concentrate as the source

✍ Mary-Anne Kedda; Michael C. Kew; Richard J. Cohn; Stephen P. Field; Rosemary Sch 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 656 KB

We report an outbreak of hepatitis A in nine South African hemophiliacs treated exclusively with infusions of factor VIII concentrate. The solvenudetergent (S/D) method (which does not inactivate nonenveloped viruses) was used for virus eradication. In three of six patients studied at a molecular le